Author Archives: fdoonan

Session 10

Jensen et al., (2014) EasyClone: method for iterative chromosomal integration of multiple genes in Saccharomyces cerevisiae Key findings: In their study Jensen et al. 2014 present a method to simultaneously integrate several genes into the genome of Saccharomyces cerevisiae by … Continue reading

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Session 9

Almeida et al., (2014) A Gondwanan imprint on global diversity and domestication of wine and cider yeast Saccharomyces uvarum Key Findings: In a previous work from the same team of Professor Sampaio, they observed a sympatric relationship between Saccharomyces uvarum … Continue reading

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Session 7

Khou et al., (2015) Distributing a metabolic pathway among a microbial consortium enhances production of natural products Key findings: The aim of the group of Stephanopoulos is to reconstruct a heterologous pathway for a paclitaxel precursor in a microbial partnership. … Continue reading

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Session 6

Leber at al., (2013). Engineering of Saccharomyces cerevisiae for the Synthesis of Short Chain Fatty Acids. Key findings: The introduction of human Fatty acid synthase (FAS) and exogenous short chain thioesterases in S. cerevisiae increased in vivo caprylic acid (octanoic … Continue reading

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Session 5

Marie-Nelly et al., (2014). High-quality genome (re)assembly using chromosomal contact data Key findings: The authors of this article presented a new algorithm to assemble genome sequences. This software, called GRAAL, makes use of the reads obtained by the sequencing platforms … Continue reading

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Session 4

Matsuo et al., (2013). Coupled GTPase and remodelling ATPase activities form a checkpoint for ribosome export. Key findings: Protein biosynthesis is a very complicated, multistage process subjected to strict control. The genetic information has to be very carefully read and … Continue reading

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Session 3

Luque et al., (2014) In vivo evolution of metabolic pathways by homeologous recombination in mitotic cells. So far, engineering of metabolic pathways has relied on in vitro techniques that can lead to the production of better enzymes, for example with … Continue reading

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Session 2

Zid et al., (2014) Promoter sequences direct cytoplasmic localization and translation of mRNAs during starvation in yeast. Key findings: The authors used novel approach, ribosome profiling, to identify upregulated mRNAs during yeast starvation. Also they have found that those mRNAs … Continue reading

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Session 1

Fischer et al. (2011), Metabolic Engineering of Monoterpene Synthesis in Yeast, Biotechnology and Bioengineering. Key findings: Wild S. cerevisiae strains are – with a few exceptions for winemaking strains up to 5 µg/L – not able to produce monoterpenes. Unlike … Continue reading

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